产品货号：
GS4870
中文名称：
重组人IL-8,72a.a./CXCL8
英文名称：
Recombinant Human Interleukin-8, 72a.a./CXCL8
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 8.4kDa,a single non-glycosylated polypeptide chain containing 72 amino acids.
储存条件：冷冻（-20℃）
概述
Interleukin-8(IL-8)is encoded by the IL8 gene and produced by macrophages and other cell types such as epithelial cells.It is also synthesized by endothelial cells,which store IL-8 in their storage vesicles.There are many receptors capable to bind IL-8,the most affinity to IL-8 are receptors CXCR1,and CXCR2.As a member of the CXC chemokine family,function of IL-8 is the induction of chemotaxis in its target cells,like neutrophil granulocytes,basophils,and T-cells.IL-8(72a.a.)has a 5-10-fold higher activity on neutrophil activation,compared to IL-8(77 a.a.).IL-8 is often associated with inflammation and has been cited as a proinflammatory mediator in gingivitis and psoriasis.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人IL-8,72a.a./CXCL8，IL-8, 72a.a./CXCL8, Human，Recombinant Human Interleukin-8, 72a.a./CXCL8
储存条件：冷冻（-20℃）
概述
Interleukin-8(IL-8)is encoded by the IL8 gene and produced by macrophages and other cell types such as epithelial cells.It is also synthesized by endothelial cells,which store IL-8 in their storage vesicles.There are many receptors capable to bind IL-8,the most affinity to IL-8 are receptors CXCR1,and CXCR2.As a member of the CXC chemokine family,function of IL-8 is the induction of chemotaxis in its target cells,like neutrophil granulocytes,basophils,and T-cells.IL-8(72a.a.)has a 5-10-fold higher activity on neutrophil activation,compared to IL-8(77 a.a.).IL-8 is often associated with inflammation and has been cited as a proinflammatory mediator in gingivitis and psoriasis.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration range of 10-100ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
| 内毒素 | Less than 1EU/μg of rHuIL-8,72a.a./CXCL8 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS |
相关搜索：重组人IL-8,72a.a./CXCL8，IL-8, 72a.a./CXCL8, Human，Recombinant Human Interleukin-8, 72a.a./CXCL8